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Yeungnam Univ J Med > Volume 5(2); 1988 > Article
Yeungnam University Journal of Medicine 1988;5(2):239-246.
DOI:    Published online December 31, 1988.
A Case of Pure Red Cell Aplasia.
Myung Sook Choi, Chae Hoon Lee, Chang Ho Cheon, Kyung Dong Kim, Chung Sook Kim, Myung Soo Hyun
Pure red cell aplasia in uncommon disorder characterized by finding of anemia, absence of nucleated red blood cell in the marrow, absence of reticulocytes in the peripheral blood and normal peripheral platelet and leukocytes counts. We experienced one case of pure red cell aplasia associated with hemolytic anemia characterized by hemoglobinuria, reticulocytopenia, and erythroid hypoplasia of the bone marrow. The cause of the illness was not definitely identified, but we concluded that this patient had simultaneous occurrence of PRCA and hemolytic anemia following administration of diphenylhydantoin after craniotomy rather than virus or bacteria induced. The simultaneous occurrence of PRCA and hemolytic anemia in uncommon and the mechanism for diphenylhydantoin induced PRCA and hemolytic anemia is unclear.


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