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Yeungnam Univ J Med > Volume 33(1); 2016 > Article
Yeungnam University Journal of Medicine 2016;33(1):68-71.
DOI: https://doi.org/10.12701/yujm.2016.33.1.68    Published online June 30, 2016.
Tumoral calcinosis and calciphylaxis treated with subtotal parathyroidectomy and sodium thiosulphate.
Hyunjeong Cho, Yongjin Yi, Eunjeong Kang, Seokwoo Park, Eun Jin Cho, Sung Tae Cho, Rho Won Chun, Kyu Eun Lee, Kook Hwan Oh
1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. ohchris@hanmail.net
2Department of Internal Medicine, Hongseong Medical Center, Hongseong, Korea.
3Dr. Chun & Cho's Medical Clinic & Dialysis Center, Seoul, Korea.
4Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Abstract
Tumoral calcinosis (TC) is a condition resulting from extensive calcium phosphate precipitation, primarily in the periarticular tissues around major joints. Calciphylaxis is a fatal ischemic vasculopathy mainly affecting dermal blood vessels and subcutaneous fat. This syndrome is rare and predominantly occurs in patients with end-stage renal disease. Here, we report on a rare case involving a patient with TC complicated with calciphylaxis. Our patient was a 31-year-old man undergoing hemodialysis who presented with masses on both shoulders and necrotic cutaneous ulcers, which were associated with secondary hyperparathyroidism, on his lower legs. He underwent subtotal parathyroidectomy, and sodium thiosulfate (STS) was administered for 27 weeks. Twenty months after beginning the STS treatment course, he experienced dramatic relief of his TC and calciphylaxis.
Key Words: Tumoral calcinosis, Calciphylaxis, Parathyroidectomy, Sodium thiosulphate
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