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Yeungnam Univ J Med > Volume 29(1); 2012 > Article
Yeungnam University Journal of Medicine 2012;29(1):48-53.
DOI:    Published online June 30, 2012.
Huge Hepatocellular Carcinoma Abruptly Developed within 3 Months.
Sang Hyuk Lee, Byung Ik Kim, Chang Uk Chon, Ki Bae Bang, Eun Haeng Jeong, Jeong Yeon Seo, Eun Hye Park, Ji Soo Seol
Departments of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, Korea.
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths in South Korea. To decrease its mortality rate, its early detection is very important. Screening for HCC detection has been accepted as the management modality for patients with chronic liver disease. Reported herein is a case involving the marked rapid growth of HCC detected at an advanced stage in a screening test with a 3 months interval. A 49-year-old male patient with chronic hepatitis B was admitted to the hospital due to a liver mass detected on CT scan. The patient underwent a first CT scan 3 months earlier, and no tumor was detected. Follow-up CT scan was performed and showed a 9.1 cm HCC with portal vein thrombosis. Percutaneous liver biopsy was performed, and the diagnosis of hepatocellular carcinoma was confirmed. In the pertinent guidelines, the recommended screening interval for HCC is 6-12 months, but the screening interval and additional diagnostic methods should be considered due to the variation in the HCC growth rate according to the patient's clinical characteristics.
Key Words: Hepatocellular carcinoma, Cancer screening test


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