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JYMS : Journal of Yeungnam Medical Science

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HOME > J Yeungnam Med Sci > Volume 24(2 Suppl); 2007 > Article
Original Article Does Ulcerative Proctitis Progress to Extensive Colitis Depending on Treatment?
Youn Sun Park, Byung Ik Jang, Tae Nyeun Kim
Journal of Yeungnam Medical Science 2007;24(2 Suppl):S384-390
DOI: https://doi.org/10.12701/yujm.2007.24.2S.S384
Published online: December 31, 2007
Department of Internal Medicine College of Medicine, Yeungnam University, Daegu, Korea
Corresponding author:  Byung Ik Jang, Tel: 010-7470-7172, Fax: (053) 624-8386, 
Email: jbi@med.yu.ac.kr
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Background
:The incidence of Ulcerative colitis (UC) in Korea are low compared with those of Western countries, but have been increasing rapidly during the past decades. Clinical characteristics of UC in Asian population are not well recognized. Therefore we investigated the clinical course of UC in Korea. Material and Methods:We retrospectively analyzed 211 UC patients first diagnosed and long term follow up colonoscopic examined at Yeungnam University Medical Center between 1989 and 2006. We reviewed extension of lesion by follow up endoscopic finding and symptom depend on treatment.
Results
:The male to female ratio was 1 : 1.1 and the median age at diagnosis was 46.0 years (range, 17-83 years). At diagnosis, proctitis was noted in 70 patients (33.2%), proctosigmoiditis in 40 (19%), left-sided colitis in 22 (10.4%), extensive colitis in 79 (37.4%). Further extension in the colon was most frequently observed in patients with proctitis (22.8%). In the patients initially diagnosed with proctitis, 28.6% of the patients were not taking any kind of medication for UC and 54 patients (77%, treatment group 34 patients, untreatment group 20) had not progressed during the observation period (56 months, range 2-193 months). The maximal extent of the disease was not affected by treatment (P = 0.99).
Conclusion
:The initial extent of the disease in Korean UC patients was similar to that found in other Western studies. In the present study, most of limited UC(proctitis, proctosigmoiditis, 77-82%) did not progress to extensive colitis regardless of treatments, but large scale multicenter analysis was needed.

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